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Predicting Abnormal Coagulation in Ischemic Stroke: Reducing Delay in rt-PA Use Neurol 67:1665-1667, Gottesman,R.F.,et al, 2006 See this aricle in Pubmed Article Abstract Normal prothrombin time (PT) and partial thromboplastin time (PTT) are recommended for administration of recombinant tissue-plasminogen activator (rt-PA) in stroke, but waiting for results can delay use. We examined the charts of 365 stroke patients to assess predetermined risk factors associated with elevated PT/PTT. Elevated PT/PTT can be predicted in patients taking warfarin or heparin/heparinoid or on hemodialysis, according to emergency department triage, with 100% sensitive and 94.7% specificity. These results could be applied to rt-PA candidates and reduce potential delays.

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(click to filter results - removes previous filter) cerebrovascular accident cerebrovascular accident,thrombolytic agents in treatment coagulopathy fibrinolytic agents fibrinolytic agents,contraindications fibrinolytic therapy,timing of administration partial thromboplastin time partial thromboplastin time,prolonged prothrombin time tissue plasminogen activator,intravenous

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